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Chemistry and Applied Biological Sciences

South Dakota Mines Creates New Center for Sustainable Solutions

Sadie Tornberg, who is completing her masters in atmospheric and environmental sciences at South Dakota Mines, spent part of her summer in the backcountry of Montana and Idaho studying water quality on the Kootenai River. Research like this is one example of many that fall under the new Center for Sustainable Solutions at Mines.

South Dakota Mines has created a new multidisciplinary Center for Sustainable Solutions. The center will be a hub for research and development around sustainability including water quality, emerging contaminants, agriculture, infrastructure, carbon capture, biofuels, bioplastics, environmental stewardship and more.

“As society faces increasingly complex problems, providing sustainable solutions requires integrative partnerships and approaches that build convergence of many disciplines with research and support for stakeholders at all levels,” says Lisa Kunza, Ph.D., an associate professor in the Department of Chemistry, Biology and Health Sciences and the director of the new center at Mines.

In the last five years leading up to establishing the Center for Sustainable Solutions, there have been nearly 50 faculty and researchers from eight departments on campus participating in the efforts. “As an institution of higher education, it is imperative to have many graduate and undergraduate students trained in the collaborative environment that the Center for Sustainable Solutions provides while tying the innovative efforts to support the needs of the people,” says Kunza.

The center will help serve the needs of a wide range of partners, from assisting the Department of Defense (DoD) in mitigating emerging ...

Last Edited 8/29/2023 08:57:58 PM [Comments (0)]

South Dakota Mines Forges New Partnership with Peruvian University thanks to 100,000 Strong in the Americas Innovation Fund

Dr. David Dixon, a South Dakota Mines professor in the Karen M. Swindler Department of Chemical and Biological Engineering, stands with Ryan Rowlands, director of Public Diplomacy Office in the Bureau of Western Hemisphere Affairs at the U.S. Department of State, on an early February visit to the U.S. Chief of Mission’s Residence in Bogotá, Colombia.

South Dakota Mines and the Universidad Peruana de Ciencias Aplicadas in Lima, Peru, (UPC Peru) were awarded a grant from the 100,000 Strong in the Americas Innovation Fund to build a partnership that includes a student exchange that builds technical, intercultural and soft-skills training that are needed to improve water quality in Peru.

This program will increase student and faculty collaboration, mobility and cross-cultural skills in the U.S. and Peru. It will also hone student skills via a water sanitation project for families who lack water services in the Lima district of Villa María del Triunfo, Peru.

Fog Catcher SystemCapstone design student teams and faculty from both universities will work together virtually and in-person on implementation of a fog catcher system that collects water from the air to be used for domestic purposes, irrigation of orchards and the implementation of a waste-water treatment system to be re-used for irrigation. At Mines, multidisciplinary teams of students from chemical engineering, civil and environmental engineering and other departments will be invol...

Last Edited 6/28/2023 08:17:15 PM [Comments (0)]

Corn Stalks in Space: NASA Next-Gen Battery Breakthrough Fueled by Multidisciplinary Collaboration at South Dakota Mines

Weibing Xing, (second from left) and his research team (from left to right: Gulam Smdani, Weibing Xing, Haiden Studer, Wahid Hasan, Amir Razzaq, Chris Poches and Salman Khan Mithil) in a next-generation battery research laboratory at South Dakota Mines.

South Dakota Mines has received a new $750,000 NASA EPSCoR grant to fund research into the next generation of lithium-sulfur batteries for use in space technology. The grant comes following a breakthrough on campus into a new polymer-biocarbon cathode coating made from corn stalk residues that stabilizes next-generation battery chemistry to nearly double the charging capacity of current technology.

A press release from NASA on this research states, “Improving the power capacity and life of batteries could help NASA power rockets, spacecraft, and habitats on the Moon, and eventually, Mars.”

Shende research team 2023The breakthrough began with the work of Rajesh Shende, Ph.D., on finding new uses for biorefinery waste leftover from the bioproc...

Last Edited 6/28/2023 08:04:52 PM [Comments (0)]

Mines Joins Research Collaboration to Develop Spray-On Bioplastics for Use in Farming

Tanvi Govil, a doctoral student at Mines, helped discover a microbe that eats corn stalks and produces environmentally friendly bioplastic without costly pre-treatments. This patent-pending breakthrough technology, developed at Mines’ CNAM-Bio Center, is a key component in the BioWRAP project.

South Dakota Mines researchers are part of a new $6 million grant from the National Science Foundation (NSF) to develop bioplastics for use in agriculture over the next four years.

The project, called Bioplastics with Regenerative Agricultural Properties, or BioWRAP, includes a research team at Mines working alongside a principal investigator at Kansas State University and researchers at the University of Nebraska-Lincoln.

Traditional specialty crop production, like organic agriculture, often use petroleum-based plastic sheets to cover the ground. Conventional plastics leave microplastic residues which contaminate the environment and increase stormwater runoff. This project aims to reduce the use of plastics, herbicides, fertilizers and associated environmental impacts in agricultural production by creating an all-in-one bioplastic system that can better manage weeds, add nutrients to soils, improve soil and plant health, and save water.

“This is exciting research to see unfold on campus as it can have a major benefit for farmers in South Dakota and across the nation. Kudos to Mines researchers for seeking solutions that are both cost saving for our ag producers and health...

Last Edited 9/13/2023 06:15:49 PM [Comments (0)]

Women in Science & Technology I: Making History

Ada Lovelace, Lady Jane Franklin and Rachel Carson are three women in STEM who helped make history.

Women have made many important and fascinating contributions to science and technology. When asked to name a woman scientist, however, too often the only woman people can think of is Marie Curie. She is of course a very important part of women’s history in science, but she’s only one of many women influencing science and engineering!

To celebrate Women’s History Month and help kick off the STS blog, this is the first of three posts about women in science & technology who are not Marie Curie. For this series, members of our STS faculty have chosen women in science and technology – both historical and contemporary – who they think are worth our attention. In this post, we share three women in science and technology who helped make history.

Ada Lovelace – selected by Erica Haugtvedt

Ada Lovelace wrote arguably the first computer program for Charles Babbage’s hypothetical mechanical computer, the “analytical engine.” She was the only legitimate daughter of George Gordon, Lord Byron, the famous Romantic poet, peer, and politician. Lovelace’s parents separated when she was an infant; the estrangement was bitter. Lovelace’s mother, herself considered a youthful prodigy in mathematics, committed herself to educating Lovelace in mathematics and science as an antidote against Byron’s poetic influence. Lovelace, however, remained attached to the legacy of her father and would not only name he...

Last Edited 3/23/2021 09:37:55 PM [Comments (0)]

University Epidemiologists Debunk Myths Related to COVID-19 Vaccine

Two epidemiologists at South Dakota Mines, Elizabeth Racz, Ph.D., MPH (left) and Christine Mathews, Ph.D., MPH, (right) say myths circulating online about the COVID-19 vaccine may reduce the number of people who get vaccinated which could prolong the pandemic.

Epidemiologists at South Dakota Mines say misinformation about the COVID-19 vaccine currently circulating on the internet may frighten some people away from becoming inoculated. 

Dr. Elizabeth Racz, MPH, says falsehoods include the accusation that corners were cut in development of this vaccine. “On the contrary,” Racz says. “The Food and Drug Administration’s decision to grant the emergency use authorization for the SARS-CoV-2 vaccine was based on scientific data. The process was made a priority — as vaccine development goes it was definitely done quickly, but not sloppily.”

Racz adds that there is no evidence to substantiate internet rumors. She says fetal stem cells were not used in COVID-19 vaccine or its development. The vaccine will not cause infertility and won’t change DNA. “The vaccine helps your body recognize and respond to the virus. The vaccine teaches your immune system. Once your immune system has learned to detect the virus it can act more quickly and accurately to eliminate it. Your immune system also has ‘memory’ cells. These specialized cells remember how to protect you from the disease in the future — in this case COVID-19,” Racz says. 

Dr. Christine Mathews, MPH, explains that the mRNA vaccine cannot give anyone COVID-19. “mRNA, like DNA, is a nucleic acid found in all living cells. DNA is located in the nucleus of the cell and contains all the instructions necessary for making proteins in the body. Howe...
Last Edited 1/26/2021 03:03:10 PM [Comments (0)]

South Dakota Mines receives $1.3 Million Grant for New Scanning Electron Microscope to Benefit Research and Industry

South Dakota Mines is installing a new Scanning Electron Microscope in the university’s Engineering and Mining Experiment Station.

South Dakota Mines is installing a new Scanning Electron Microscope (SEM) in the university’s Engineering and Mining Experiment Station (EMES) thanks to a $1.3 million grant from the National Science Foundation. The new microscope is just one of many state-of-the-art scientific instruments inside the recently expanded EMES which serves high-tech industry alongside university researchers across the state.

The powerful SEM microscope is a centerpiece of the EMES. It allows researchers to perform high resolution imaging, chemical analysis and sample manipulation for various materials at scales ranging down to 100,000 times smaller than the width of a human hair. The new microscope is a critical resource for a wide variety of research across multiple disciplines.

“The SEM is the most heavily used research instrument on campus,” says Grant Crawford, Ph.D., the director of the Arbegast Materials Processing and Joining Laboratory at Mines and an associate professor in the Department of Materials and Metallurgical Engineering.

The new SEM is equipped with a focused ion beam that dramatically expands its capability over the old system. The ion beam allows researchers to extract samples for separate analysis and cr...

Last Edited 1/19/2021 04:07:49 PM [Comments (0)]

South Dakota Mines EMES Facility Expands to Include Array of Instruments with Environmental Applications

Dr. Scott Beeler uses a gas chromatograph-mass spectrometer (GC-MS) in the Engineering and Mining Experiment Station (EMES) at South Dakota Mines. The GC-MS is used to identify and quantify organic compounds with applications in a wide range of fields such as environmental monitoring, medicine, and oil and gas.

The Engineering and Mining Experiment Station (EMES) at South Dakota Mines has begun overseeing the operation and maintenance of instrumentation within the Shimadzu Environmental Research Laboratory (SERL).

The EMES was founded on the Mines campus in 1903 with a mission to serve mining industry research. Today the mission has expanded to include a much broader range of academic and industry needs with a wide array of scientific equipment that is utilized by industry professionals and university researchers across the region. The EMES has seen equipment investments by the South Dakota Board of Regents and the National Science Foundation totaling more than $2.8 million since 2011. The EMES website lists the range of scientific equipment available for academic research and industry use including the Shimadzu instrumentation.

The SERL was established in 2015 in partnership with Shimadzu Scientific Instruments by Lisa Kunza. Ph.D., associate professor in the Department of Chemistry Biology and Health Sciences at Mines. The SERL is a multidisciplinary research facility that contains a suite of state-of-the-art instrumentation with a focus on environmental applications. SERL instruments enable the chemical characterization of a wide range of sample types including natural waters, biological materials, roc...

Last Edited 9/28/2023 08:49:11 PM [Comments (0)]

Mines Mechanical Engineering Alumnus Conducts Research on Dental-Related Infections

Joree Sandin, 2018 South Dakota Mines mechanical engineering graduate, participated in research in the area of antibiotic resistant infections as a master’s student at the University of Kentucky.

As a mechanical engineering graduate from South Dakota Mines, Joree Sandin never expected to do medical research, but the 2018 graduate has spent the past two years focused on antibiotic resistant infections. 

“Three or four years ago, as a mechanical engineering major at Mines, I would never have imagined that I would have gained this experience … my car took a random exit toward this bio world and I’m so glad it did,” she says. 

Sandin recently completed her master’s in mechanical engineering from the University of Kentucky College of Engineering. She returned to Mines in October to co-present the research seminar, “A Mechanical Engineer’s Approach to Bacterial Infections,” alongside Dr. Martha E. Grady, assistant professor in mechanical engineering at UK and lead researcher on the work. 

The UK research Sandin has been a part of focuses on biofilm formations, specifically in dental care.  

Biofilms are a collection of microorganisms that grow on surfaces. The microorganisms that make up biofilms can include bacteria, protists and fungi. “Biofilms are really everywhere,” Sandin say...

Last Edited 12/3/2020 08:32:39 PM [Comments (0)]

SD Mines Researchers Pioneer New Methods to Turn Biorefinery Waste into Valuable Products

Vinod Amar, Ph.D., one of the research scientists working on the project is shown here in his lab.

Shende Research Team 2A research team at the South Dakota School of Mines & Technology is beginning work on pilot scale testing of new methods that turn biorefinery waste into valuable products. The waste biomass or byproducts generated by ethanol plants and other biorefineries, such as corn stover, are normally thrown away—but finding cost-effective means of using this waste to make new products will generate extra revenue for the facilities, help lower fuel costs, reduce carbon emissions, and ultimately help farmers.

“This is one more way SD Mines is pioneering research that helps the environment while increasing efficiency and profit margins for our industry partners.  This is the kind of work that can have a positive impact on the economy of South Dakota,” says SD Mines Vice President of Research Ralph Davis, Ph.D.

Rajesh Shende, Ph.D., professor in the chemical and biological engineering department at SD Mines, is leading the research. This work began in Shende’s lab with a $2.16 million grant from the Department of Energy (DOE) Bioenergy Technologies Offi...

Last Edited 10/4/2021 03:31:29 PM [Comments (0)]

2D Materials, Biofilm and Microbial Research at SD Mines Brings in $32 Million in National Science Foundation Grants

Govind Chilkoor, Ph.D., an SD Mines research scientist, examines a biofilm on a steel sample following its exposure to corrosive bacteria. Dr. Chilkoor is working to develop new ultrathin two-dimensional (2D) coatings that resist microbial corrosion. His research is one component of a newly announced $20 million NSF grant titled “Building on the 2020 Vision: Expanding Research, Education and Innovation in South Dakota.”

In the past three years, the National Science Foundation (NSF) has awarded  $32 million in funding for research led by faculty at South Dakota School of Mines & Technology that expands human understanding of the microbial world. Much of the research focuses on the environment microbes occupy when they attach to surfaces and create what is commonly known as a biofilm.

The broad range of studies on microbes and biofilms, funded by these grants, has a wide potential for applications across many sectors of industry and society including energy generation, new medicines, wastewater purification, agriculture, corrosion resistance, new materials and reduction of greenhouse gas emissions.

The research effort of the newly announced $20 million NSF grant titled “Building on the 2020 Vision: Expanding Research, Education and Innovation in South Dakota” will be led by researchers at SD Mines, SDSU and USD. The funding was awarded through the South Dakota Established Program to Stimulate Competitive Research (SD EPSCoR) and the South Dakota Board of Regents. The state of South Dakota is providing $4 million in matching funds for the grant. The Governor’s office of Economic Development and Board of Regents are providing $3 million and there is ...

Last Edited 10/17/2023 05:18:47 PM [Comments (0)]

Termite Mounds Hide Secrets to Sustainable Buildings of the Future

Andrea Surovek, Ph.D., a research scientist from SD Mines’ Department of Mechanical Engineering, standing next to a termite mound in Namibia.

South Dakota School of Mines & Technology has been awarded $475,000 from the National Science Foundation to study how termites construct mounds with the idea that humans might one day adapt the energy-efficient homebuilding techniques of the insects. The award is a follow-up to a previous grant by NSF of $300,000.

Mines faculty researchers spent time in the African country of Namibia to study the shape and function of termite mounds. The mounds are resilient and naturally energy efficient. Their intricate interior designs provide ventilation and temperature regulation throughout what can easily be a 15-foot-tall home for a single colony of 2 million termites. 

“An understanding of the natural processes involved in termite mound construction and function can be adapted to inform engineering applications related to the construction of man-made structures that require zero or minimal energy inputs,” said the NSF award letter.

Co-principal investigator Andrea Surovek, Ph.D., a research scientist from SD Mines’ Department of Mechanical Engineering, has lead research that examined hundreds of slices of a termite mound and has developed three-dimensional models of numerous mounds using ...

Last Edited 10/30/2018 09:21:47 PM [Comments (0)]

Powerful Bugs: Harnessing the Electric Eels of the Microbial World

“We’re studying the electric eels of the microbial world,” says Navanietha Krishnaraj, Ph.D., a research scientist in the Chemical and Biological Engineering department at SD Mines. - Photo Credit NOAA

Researchers at the South Dakota School of Mines & Technology are studying ways to harness electricity generated by a unique set of microbes. 

 

“We’re studying the electric eels of the microbial world,” says Navanietha Krishnaraj, Ph.D., a research scientist in the Chemical and Biological Engineering department at SD Mines.

 

Researchers, such as Venkata Gadhamshetty, Ph.D., an associate professor in the Civil and Environmental Engineering department at SD Mines, and his team including Namita Shrestha, Ph.D., are working on maximizing the efficiency of what’s known as bioelectrochemical systems. By understanding the right combination of microbes and materials it’s possible to harness clean energy for widespread use in various applications.

 

Possible outcomes of this research include new ways to generate electricity and treat solid waste during NASA space missions, the ability for a wastewater treatment plants to help generate electricity while turning effluent into clean water, a new way to clean saline wastewater generated in oil drilling operations, and better ways to turn food waste, like tomatoes and corn stover into e...

Last Edited 9/28/2023 08:15:07 PM [Comments (0)]

SD Mines Researchers Trace Pollution from Historic Northern Hills Mine Tailings Hundreds of Miles Downstream

Students taking part in research on this project include Bryce Pfiefle, the lead author of this paper, who graduated from SD Mines with a master’s degree in geological engineering.

The Black Hills of South Dakota was once home to the largest underground gold mine in North America – the Homestake Mine. Following its closure in 2002, the mine was turned into the Sanford Underground Research Facility. But, newly published research shows evidence of the past mining activities can still be found hundreds of miles downstream.

The history of gold mining in the northern Black Hills dates back about 130 years. During the first to middle part of the 20th century, about 100-million tons of mine tailings went down Whitewood Creek and into the Belle Fourche, Cheyenne and Missouri rivers. Research by a group of scientists, including James Stone, Ph.D., a professor of Civil and Environmental Engineering at the South Dakota School of Mines & Technology, along with others at the USGS Dakota Water Science Center show elevated levels of arsenic and other contaminants in these historic mine tailings.  

“The concentrations in the pore waters and sediments were quite high for arsenic in some sampling sites,” says Stone. 

In the 1980s, mine tailings along Whitewood Creek, found to contain arsenic, mercury and other pollutants, became an EPA Superfund Site. That clean-up project was completed in the ...

Last Edited 10/3/2023 04:41:37 PM [Comments (0)]

Engineering an End to Back Pain

Marit Johnson, a PhD candidate at SD Mines, is focusing her research on intervertebral discs in the lower back.

There is a good chance you are sitting down right now. It’s possible you’ve been sitting all day, or maybe you’ve even been sitting every day for the last few decades.

“There is a trend in the 21st century that 80 percent of our jobs require sitting, and it’s even more so when you include leisure time,” says Marit Johnson (CE 96), a PhD candidate in biomedical engineering at SD Mines.

You may guess that spending all this time in a chair is not so good for your health. In fact, research is now showing prolonged sitting may contribute to lower back pain. “Eighty percent of us will experience back pain in our lifetime,” says Johnson. "If your job requires long hours in a chair, back pain can be a real issue."

Johnson’s research is focused on the intervertebral discs of the lower back. These discs are in between the vertebrae, or bones, of the spine, and their softer tissue provides cushion and flexibility. They are key components of a healthy and functional spine.

Research shows that intervertebral discs need to exchange fluid to maintain a healthy environment, similar to how our bodies need breathing to exchange carbon dioxide with oxygen for our survival. “Typically, when we wake up in the morning we’re taller,” says Johnson. At night when we sleep the discs pull in fluid and they expand. As the day goes on,...

Last Edited 7/30/2018 07:35:16 PM [Comments (0)]

Growing Copper Deep Underground: SD Mines Plays Integral Role in Successful MAJORANA DEMONSTRATOR Experiment

Much of the experiment’s copper is processed underground to remove both natural radioactivity (such as thorium and uranium) and radioactivity generated above ground when cosmic rays strike the copper. Electroforming relies on an electroplating process that over several years forms the world’s purest copper stock. Ultrapure copper is dissolved in acid and electrolytically forms a centimeter-thick plate around a cylindrical stainless-steel mandrel. Any radioactive impurities are left behind in the acid. Here collaborator Cabot-Ann Christofferson of the South Dakota School of Mines & Technology measures the thickness of copper pulled from an electroforming bath. Credit: Sanford Underground Research Facility; photographer Adam Gomez

The collaborators working on the MAJORANA DEMONSTRATOR have published a study in the journal Physical Review Letters showing the success of the experiment housed in the Sanford Underground Research Facility (SURF). The success of the MAJORANA DEMONSTRATOR opens the door for the next phase of the experiment and sets the stage for a breakthrough in the fundamental understanding of matter in the universe. 

The experiment, led by the Department of Energy’s Oak Ridge National Laboratory, involves 129 researchers from 27 institutions and six nations. The South Dakota School of Mines & Technology was an integral part in facilitating the underground laboratory space at SURF and helped lead the effort to build the ultra-pure components needed to construct a successful experiment. 

“The goal was to demonstrate the feasibility and capability to build a larger one-ton experiment,”  says Cabot-Ann Christofferson, the Liaison and a Task Leader within the  MAJORANA Collaboration at the Sanford Underground Lab and an...

Last Edited 6/28/2018 07:05:55 PM [Comments (0)]

The Gas Cube – Turning Remote Base Waste Into Energy

The Gas Cube is a compact reactor that can turn waste into methane gas.

Cows, as many people know, have four stomachs. Cows also generate lots of methane.  So, if your goal is to describe a machine that turns food waste and cardboard into methane gas, the bovine digestive system is an analogy that makes some sense.  

“Our reactor is some ways a two-stomach cow,” says Jorge Gonzalez-Estrella, a post-doctoral research associate in the Chemical and Biological Engineering Department at Mines.

Gonzalez-Estrella is one of the researchers working on the Gas Cube project.  The semi-trailer-sized reactor is much larger than a cow, but it’s still portable. It’s one of the projects in development at Mines aimed at turning a range of remote base waste into energy. This is all thanks to a $4.8 million grant from the United States Air Force, $1.2 million of which funds the Gas Cube.  A remote Air Force Base can produce lots of waste. The Air Force seeks to save waste handling and fuel costs at mission-based remote bases. This is a challenge that the Gas Cube is designed to overcome. 

How does it work?  Back to the cow analogy. At the Gas Cube’s input, or mouth, a shredder grinds up the solid cardboard or food waste and deposits it in chamber number one. This is sort of like a cow chewing and swallowing its food. Then in that first chamber, or stomach number one, hydrolytic microorganisms break down the mix of food waste and cardboard into sugars, and fermenting microbes then break up those su...

Last Edited 8/29/2023 09:01:18 PM [Comments (0)]

Microscopy Trifecta Examines How Cells Engulf Nutrients, Viruses

As part of her doctoral research at the South Dakota School of Mines & Technology nanoscience and nanoengineering program, Amy Hor examines chemically fixed cells using correlated fluorescence and atomic force microscopy. She worked under the direction of professor Steve Smith. The collaborative research, which also involved microscopy teams from South Dakota State University and the National Institutes of Health, showed that membrane bending occurs at all stages of clathrin assembly.

Scientists have a better understanding of a mechanism that allows cells to internalize beneficial nutrients and not-so-beneficial viruses, thanks to collaboration among researchers from two South Dakota universities and the National Institutes of Health.           

South Dakota State University associate professor Adam Hoppe, South Dakota School of Mines & Technology professor Steve Smith and NIH scientists Justin Taraska and Kem Sochacki combined three unique types of microscopy to track how a protein called clathrin triggers cell membrane bending. They found that clathrin, which creates a honeycomb shaped scaffold on the cell membrane, has an unexpected amount of plasticity when pinching off small portions of the cell membrane. Their work was published in the Jan. 29, 2018, issue of Nature Communications.

Hoppe and Smith work collaboratively through the South Dakota BioSystems Networks and Translational Research (BioSNTR) center, which is funded through the South Dakota Research Innovation Center program and the National Science Foundation’s Established Program to Stimulate Competitive Research program. A greater understanding of how cells internalize material will help BioSNTR researchers working with Sioux Falls-based SAB Biotheraputics to develop new alternative treatments for influenza.

The contributions of NIH scientists Justin Taraska and Kem Sochacki were made possible through a federally fund...

Last Edited 4/26/2018 07:37:40 PM [Comments (0)]

SD Mines Researchers Pioneer New Testing Method That Identifies Pathogenic Potential in South Dakota Waterways

The project included over 1000 DNA extractions from bacteria in water samples taken out of Rapid Creek and the Big Sioux River over a two-year period.

Researchers at the South Dakota School of Mines & Technology have completed a groundbreaking study on harmful bacteria found in two important South Dakota waterways. The research, undertaken by Ph.D. candidate Kelsey Murray, found genes related to harmful E. coli in parts of the Big Sioux River and Rapid Creek.  

Public health officials often test streams and rivers for fecal coliform bacteria or E. coli, as this group of bacteria can be an indicator of pollution from animal or human waste. But, not all forms of E. coli are dangerous to humans; in-fact most are harmless. This study pioneered new testing methods that more accurately assess the public health risk from fecal contaminated waters by singling out and testing for genes associated with harmful forms of E. coli, including Shiga-toxigenic E. coli (STEC). 

Murray’s research, performed under Linda DeVeaux, Ph.D., and Lisa Kunza, Ph.D., is titled “Path-STREAM: Development and Implementation of a Novel Method for Determining Potential Risk from Pathogenic Bacteria in Surface Water Environments” Path-STREAM stands for Pathogenicity Profiling: Shiga Toxins and Related E. coli Attributes identification Method.

The project included over 1000 DNA extractions from bacteria in water samples taken out of Rapid Creek and the Big Sioux River over a two-year period. The effort built a method to identify the pathogenic genes associated with STEC and other...

Last Edited 10/3/2023 04:27:00 PM [Comments (0)]

Killing Anthrax

Lori Groven, PhD, an assistant professor in the chemical and biological engineering department at SD Mines, is pioneering new ways to fight biological weapons.

In the weeks following the September 11th attacks, a series of letters containing anthrax spores arrived at media outlets and the offices of US Senators Tom Daschle and Patrick Leahy. The acts of bioterrorism gripped the nation in confusion, anger, and fear. Scores were hospitalized and five people died. It was a senseless tragedy. But, it could have been much worse.

“Ten grams of anthrax spores could wipe out all of Washington, DC, and the surrounding area,” says Lori Groven, (BS ChE, MS ChE, PhD Nanoscience and Nanoengineering). “Biological weapons are scary for everybody, because it takes so little to do so much damage,” she adds. The minimum lethal dose for anthrax is estimated to be 5-10,000 spores, and one gram of anthrax contains well over a trillion spores. 

Groven is a research scientist and assistant professor in the chemical and biological engineering department at Mines. She and her team are part way through a five-year half-million-dollar grant from the Defense Threat Reduction Agency. The research has led to new materials and methods for combating bioterrorism.

One challenge Groven and her team have faced is the instability of the chemicals currently used to neutralize biological weapons. These compounds, or biocides, are made up mostly of a fuel and oxidizer (iodate) powder. They have a very short shelf life. “This stuff doesn’t age very well," says Groven. “If you put it out on the counter,...

Last Edited 8/29/2023 09:01:41 PM [Comments (0)]

SD Mines Researchers Hope to Use Sanford Lab Extremophiles to Create Low-Cost Renewable and Biodegradable Polymers

Courtney Carlson, a senior majoring in Chemical Engineering at SD Mines (right) and researcher Navanietha Krishnaraj Rathinam, Ph.D., (left) work in the Chemical and Biological Engineering and Chemistry (CBEC) building at SD Mines. Carlson and Krishnaraj Rathinam are using benchtop reactors in the lab to perform CNAM-Bio research that seeks to optimize and scale-up the manufacturing of biopolymers from lignocellulosic biomass using extremophiles. The center is a scanning electron microscope image of the bacteria the research team are studying.

A team of researchers with the Composite and Nanocomposite Advanced Manufacturing – Biomaterials Center (CNAM), led by David Salem, Ph.D., at the South Dakota School of Mines & Technology are using microbes that were discovered deep underground in the Sanford Underground Research Facility (SURF) in an attempt to make low-cost plastics that are renewable and biodegradable.

“Most commercial polymers, or plastics are petroleum based which is a non-renewable resource,” says Salem. The team is working to find ways to mass manufacture low-cost plant based plastics and composites. “A problem with bio-based polymers is they are expensive, and one goal of this center is to use genetically engineered microbes to help reduce the cost of manufacturing these kinds of plastics,” says Salem. “Another goal is to engineer the properties of the biopolymers and biocomposites to serve a wide range of commercial applications.”

There is a huge potential for new green-based manufacturing jobs in the area if the center succeeds in developing mass manufacturing techniques for turning plants into low-cost bio-based polymers.

“The top ten petroleum based polymers make up about a $500-billion global market,” says Salem. “These biopolymers potentially can cover the whole range of properties of those.”

A group, led by Rajesh Sani, Ph.D., from SD Mines’ Department of Chemical & Biological Engineering, have isolated th...

Last Edited 6/28/2019 01:53:45 PM [Comments (0)]

Mines Researchers Study Kootenai River Pollutants in Montana, Other Areas

South Dakota Mines student Emily Stickney conducts research on pollutants in the Kootenai River in Montana

A recent award by the U.S. Army Corps of Engineers is funding South Dakota School of Mines & Technology research on how changes in land use increase pollutants and influence the health of the Kootenai River and Lake Koocanusa in Montana, Idaho and British Columbia.

Recent land use changes in the Kootenai River watershed include increased coal mining and alterations to agricultural practices.

Dr. Lisa Kunza of the Department of Chemistry & Applied Biological Sciences, is heading a collaborative research team that includes students, other university partners, and agency collaborators. The team has already received $160,000 and is expecting to receive up to $400,000 for its efforts over the next five years.

Selenium and nitrate loads are on the rise in the Kootenai River as it enters Lake Koocanusa. Selenium is a metal found in natural deposits and may be exposed during mining activity. In 2012 alone, selenium loads into the river exceeded 29,000 pounds, a five-fold increase since 1992. There is heightened concern about possible buildup of selenium in fish tissue. Nitrate loads have increased substantially as well and may alter the resources available for fisheries. 

Endangered Kootenai White Sturgeon and other organisms in the river and reservoir could also be affected by the pollutants.

Emily Stickney from Boise, Idaho, is among the undergraduate and graduate student researchers ...

Last Edited 1/17/2017 04:45:02 PM [Comments (0)]

Research Inquiries

For inquiries related to South Dakota Mines Research, contact:

Research Affairs

South Dakota Mines
501 E. St. Joseph Street
Vanderboom Laboratory for Entrepreneurial Research (V-LAB)
Rapid City, SD  57701

(605) 394-2493